Preparation of High Performance Brush-Like Zinc Oxide Mesocrystals and Its Reinforcing Effect on Properties of Resin Composites

Abstract

Abstract: The inorganic filler is the main component of dental resin composite, which is very important for the properties of resin composite. In this paper, ZnO mesocrystals with porous and hierarchical structure were achieved by a thermal hydrolysis method using gum arabic as structure-directing agent. The thickness and diameter of the synthesized ZnO mesocrystals were about 1.2 μm and 1.0 μm. The amorphous silica in a thickness of 4~6 nm was uniformly coated on the surface of ZnO mesocrystals via the microfluidc process. ZnO mesocrystals were characterized by field-emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD) and thermogravimetric analysis (TGA). The ZnO@SiO₂ was firstly modified with 3-methacryloxypropyl trimethoxysilane (γ-MPS), and mixed with modified SiO₂ nanoparticles as co-filler. Subsequently modified inorganic particles were added into Bis-GMA/TEGDMA to prepare dental composite resin by light-curing. The mechanical testing show that the mass fraction of ZnO@SiO₂ (≤5%) could improve the mechanical properties of composite resin effectively. The silica matrix composite resin filled with 3% ZnO@SiO₂ demonstrates the best mechanical properties, among which the flexural strength, flexural modulus and compression strength increase by 12.9%, 6.6% and 3.7%, respectively, in comparison with the composite using of only SiO₂ filler. This optimal composite also exhibits superior antimicrobial activity, with antibacterial rate up to 98.7% to Streptococcus mutans. In addition, the composite resin with ZnO@SiO₂ also has better wear resistance.

Key words: dental resin, ZnO mesocrystal, mechanical property, antibacterial property

CLC Number:

TB332

QIN Yang, ZHANG Qinghong, WANG Ruili, LIU Mei. Preparation of High Performance Brush-Like Zinc Oxide Mesocrystals and Its Reinforcing Effect on Properties of Resin Composites[J]. JOURNAL OF SYNTHETIC CRYSTALS, 2021, 50(3): 548-557.

References

[1] PETERSEN P E, BOURGEOIS D, OGAWA H, et al.Theglobal burden of oral diseases and risks to oral health[J]. Bulletin of the World Health Organization, 2005, 83(9): 661-669.
[2] MUSANJE L, FERRACANE J L, FERRACANE L L.Effects of resin formulation and nanofiller surface treatment on in vitro wear of experimental hybrid resin composite[J]. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2006, 77B(1): 120-125.
[3] KARABELA M M, SIDERIDOU I D.Synthesis and study of properties of dental resin composites with different nanosilica particles size[J]. Dental Materials, 2011, 27(8): 825-835.
[4] DEMARCO F F, CORRÊA M B, CENCI M S, et al. Longevity of posterior composite restorations: not only a matter of materials[J]. Dental Materials, 2012, 28(1): 87-101.
[5] MOSZNER N, HIRT T.New polymer-chemical developments in clinical dental polymer materials:enamel-dentin adhesives and restorative composites[J]. Journal of Polymer Science Part A: Polymer Chemistry, 2012, 50(21): 4369-4402.
[6] NIU L N, FANG M, JIAO K, et al.Tetrapod-like zinc oxide whisker enhancement of resin composite[J]. Journal of Dental Research, 2010, 89(7): 746-750.
[7] KIM J W, KIM L U, KIM C K.Size control of silica nanoparticles and their surface treatment for fabrication of dental nanocomposites[J]. Biomacromolecules, 2007, 8(1): 215-222.
[8] FINLAY N, HAHNEL S, DOWLING A H, et al.The in vitro wear behavior of experimental resin-based composites derived from a commercial formulation[J]. Dental Materials, 2013, 29(4): 365-374.
[9] MITRA S B, WU D, HOLMES B N.An application of nanotechnology in advanced dental materials[J]. The Journal of the American Dental Association, 2003, 134(10): 1382-1390.
[10] Sturm E V, Cölfen H.Mesocrystals: past, presence, future[J]. Crystals, 2017, 7(7): 207.
[11] FLOQUET N, VIELZEUF D.Ordered misorientations and preferential directions of growth inmesocrystalline red coral sclerites[J]. Crystal Growth & Design, 2012, 12(10): 4805-4820.
[12] 杨士林,宋微.PASP调控球形碳酸钙沉积过程研究[J].人工晶体学报,2013,42(7):1475-1480.
YANG S L, SONG W.Study on precipitation process of spherical calcium carbonate controlled bypolyaspartic acid[J]. Journal of Synthetic Crystals, 2013, 42(7): 1475-1480(in Chinese).
[13] 张克从. 晶体结构与性能关系及其发展[J].人工晶体,1985,14(Z1):11.
ZHANG K C.Crystal structure—property relations and its developments[J]. Journal of Synthetic Crystals, 1985, 14(Z1): 11(in Chinese).
[14] TANG H, CHANG J C, SHAN Y Y, et al.Surfactant-assisted alignment of ZnO nanocrystals to superstructures[J]. The Journal of Physical Chemistry B, 2008, 112(13): 4016-4021.
[15] 刘玉玲,王瑞莉,李楠,等.ZnO介晶填料的制备及其齿科复合树脂的性能[J].无机材料学报,2019,34(10):1077-1084.
LIU Y L, WANG R L, LI N, et al.Preparation of zinc oxidemesocrystal filler and its properties as dental composite resin[J]. Journal of Inorganic Materials, 2019, 34(10): 1077-1084(in Chinese).
[16] NATALIO F, CORRALES T P,PANTHÖFER M, et al. Flexible minerals: self-assembled calcite spicules with extreme bending strength[J]. Science, 2013, 339(6125): 1298-1302.
[17] CHENG L, WEIR M D, ZHANG K, et al.Antibacterial nanocomposite with calcium phosphate and quaternary ammonium[J]. Journal of Dental Research, 2012, 91(5): 460-466.
[18] PENG J J Y, BOTELHO M G, MATINLINNA J P. Silver compounds used in dentistry for caries management: a review[J]. Journal of Dentistry, 2012, 40(7): 531-541.
[19] AYDIN SEVINÇ B, HANLEY L.Antibacterial activity of dental composites containing zinc oxide nanoparticles[J]. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2010, 94B(1): 22-31.
[20] LIU M H, TSENG Y H, GREER H F, et al.Dipole field guided orientated attachment ofnanocrystals to twin-brush ZnO mesocrystals[J]. Chemistry-A European Journal, 2012, 18(50): 16104-16113.
[21] MIAO X L, LI Y G,ZHANG Q H, et al.Low shrinkage light curable dental nanocomposites using SiO₂ microspheres as fillers[J]. Materials Science and Engineering: C, 2012, 32(7): 2115-2121.
[22] KESHMIRI M, KESLER O.Colloidal formation of monodisperse YSZ spheres: kinetics of nucleation and growth[J].Acta Materialia, 2006, 54(16): 4149-4157.
[23] WEI Y, LIU S J, XIAO Z H, et al.Enamel repair with amorphous ceramics[J]. Advanced Materials, 2020, 32(7): 1907067.
[24] KRAFT D J, VLUG W S,VAN KATS C M, et al. Self-assembly of colloids with liquid protrusions[J]. Journal of the American Chemical Society, 2009, 131(3): 1182-1186.
[25] GREER H F, ZHOU W Z, LIU M H, et al.The origin of ZnO twin crystals in bio-inspired synthesis[J]. Cryst Eng Comm, 2012, 14(4): 1247-1255.
[26] TSENG Y H, LIN H Y, LIU M H, et al.Biomimetic synthesis of nacrelike faceted mesocrystals of ZnO-Gelatin composite[J]. The Journal of Physical Chemistry C, 2009, 113(42): 18053-18061.
[27] FERREIRA C S, SANTOS P L, BONACIN J A, et al.Rice husk reuse in the preparation of SnO₂/SiO₂ Nanocomposite[J]. Materials Research, 2015, 18(3): 639-643.
[28] CHEN T M, BRAUER G M.Solvent effects on bonding organo-silane to silica surfaces[J]. Journal of Dental Research, 1982, 61(12): 1439-1443.
[29] WANG R L, BAO S, LIU F W, et al.Wear behavior of light-cured resin composites with bimodal silica nanostructures as fillers[J]. Materials Science and Engineering: C, 2013, 33(8): 4759-4766.
[30] YOSHIDA K, TANAGAWA M, ATSUTA M.Effects of filler composition and surface treatment on the characteristics of opaque resin composites[J]. Journal of Biomedical Materials Research, 2001, 58(5): 525-530.
[31] JIN J F, WEI G Y, HAO A L, et al.ZnO-AlBw-reinforced dental resin composites: the effect of pH level on mechanical properties[J]. RSC Advances, 2015, 5(33): 26430-26437.
[32] YAHYAZADEHFAR M, AROLA D.The role of organic proteins on the crack growth resistance of human enamel[J].Acta Biomaterialia, 2015, 19: 33-45.
[33] BAJAJ D, PARK S, QUINN G D, et al.Fracture processes and mechanisms of crack growth resistance in human enamel[J].JOM, 2010, 62(7): 76-82.
[34] LIU Y, TAN Y N, LEI T, et al.Effect of porous glass-ceramic fillers on mechanical properties of light-cured dental resin composites[J]. Dental Materials, 2009, 25(6): 709-715.
[35] 谢周杰,张昭,刘力伟,等.变形链球菌中的次级代谢产物及其在口腔生物被膜中的生态功能[J].生物工程学报,2017,33(9): 1547-1554.
XIE Z, ZHANG Z, LIU L, et al.Secondary metabolites from Streptococcusmutans and their ecological roles in dental biofilm[J]. Chinese Journal of Biotechnology, 2017, 33(9): 1547-1554.
[36] LEMOS J A, PALMER S R, ZENG L, et al.The biology of streptococcusmutans[J]. Microbiology Spectrum, 2019, 7(1).DOI:10.1128/microbiolspec.gpp3-0051-2018.
[37] TAM K H, DJURIŠI<inline-formula><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="Mml1-1000-985X-35-3-548"><mml:mover><mml:mrow><mml:mi mathvariant="normal">C</mml:mi></mml:mrow><mml:mrow><mml:mi>'</mml:mi></mml:mrow></mml:mover></mml:math></inline-formula> A B, CHAN C M N, et al. Antibacterial activity of ZnO nanorods prepared by a hydrothermal method[J]. Thin Solid Films, 2008, 516(18): 6167-6174.
[38] GHAZAL M, YANG B,LUDWIG K, et al.Two-body wear of resin and ceramic denture teeth in comparison to human enamel[J]. Dental Materials, 2008, 24(4): 502-507.
[39] TURSSI C P, DE MORAES PURQUERIO B, SERRA M C. Wear of dental resin composites: insights into underlying processes and assessment methods—a review[J]. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2003, 65B(2): 280-285.
[40] XING X S, LI R K Y. Wear behavior of epoxy matrix composites filled with uniform sized sub-micron spherical silica particles[J]. Wear, 2004, 256(1/2): 21-26.
[41] YESIL Z D, ALAPATI S, JOHNSTON W, et al.Evaluation of the wear resistance of new nanocomposite resinrestorative materials[J]. The Journal of Prosthetic Dentistry, 2008, 99(6): 435-443.