Synthesis, Crystal Structure, DNA Binding Ability of a New Bis-Pyridine Pendant-Arms Mn(Ⅱ) Complex

Abstract

Abstract: A new dinuclear manganese(Ⅱ) complex with bis-pyridine pendant-arms was synthesized by condensation between 3,3′-((ethane-1,2-diylbis((pyridin-2-ylmethyl)azanediyl)) bis(methylene))bis(2-hydroxy-5-methylbenzaldehyde) and 2-hydroxy-1,3-diaminopropane in the presence of manganese(Ⅱ). The complex was determined by X-ray diffraction single crystal structure analysis, and the corresponding formula is [Mn₂(C₃₇H₄₃N₆O₆)]·(ClO₄)₂. The results indicate that the complex crystallizes in monoclinic, space group P2₁/c, with a=1.096 50(19) nm, b=1.419 5(3) nm, c=3.109 4(5) nm, β=108.153(5)°. The crystal structure shows that the two manganese(Ⅱ) ions in the phenolbased macrocyclic dinuclear complex are coordinated with (N_amine)₂(N_imine)₂O₃ and (N_imine)₂O₄ sites, the corresponding geometry around each manganese(Ⅱ) center are decahedron and distorted octahedron. Two manganese(Ⅱ) centers are equivalently bridged by the phenolic oxygens and an acetate radical with the intermetallic separation of 0.331 6 nm. Moreover, the binding ability of the complex toward calf thymus DNA were analyzed by voltammetric and viscosity method, which indicate the bonding mode between them is weak intercalation.

Key words: dinuclear manganese(Ⅱ) complex, macrocyclic metal complex, crystal structure, DNA binding ability

CLC Number:

O641.4

WANG Yang, LI Ming, WU Yu, YAN Juntao, MAO Jiawei. Synthesis, Crystal Structure, DNA Binding Ability of a New Bis-Pyridine Pendant-Arms Mn(Ⅱ) Complex[J]. Journal of Synthetic Crystals, 2022, 51(7): 1220-1226.

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