吡嗪席夫碱银配位聚合物的晶体结构、发光性质和抗菌活性

人工晶体学报 ›› 2021, Vol. 50 ›› Issue (6): 1076-1081.

吡嗪席夫碱银配位聚合物的晶体结构、发光性质和抗菌活性

廖延智¹, 郭俊儿¹, 冯安生^1,2, 赖敏成^1,2, 杨超杰¹, 徐小云^1,2, 游遨¹

1.广东轻工职业技术学院分析测试中心,广州 510300;
2.仲恺农业工程学院轻工食品学院,广州 510225

收稿日期:2021-04-02 出版日期:2021-06-15 发布日期:2021-07-08
通讯作者: 游遨,博士,副教授。E-mail:2015100029@gdip.edu.cn
作者简介:廖延智(1987—),男,广东省人,实验师。E-mail:2008116079@gdip.edu.cn
基金资助:
广东省教育厅青年人才项目(2018GkQNCX033);广东省教育厅特色创新项目(2020ZDZX2077);广州市科技计划(202102021119);广东轻工职业技术学院校级项目(X20190119)

Crystal Structure, Luminescent Properties and Antibacterial Activity of Silver(I) Coordination Polymer with Pyrazine Schiff-Base Derivative Ligand

LIAO Yanzhi¹, GUO Juner¹, FENG Ansheng^1,2, LAI Mincheng^1,2, YANG Chaojie¹, XU Xiaoyun^1,2, YOU Ao¹

1. Analysis and Testing Center, Guangdong Industry Polytechnic, Guangzhou 510300, China;
2. School of Light Industry and Food, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China

Received:2021-04-02 Online:2021-06-15 Published:2021-07-08

摘要/Abstract

摘要： 利用2-乙酰基吡嗪和异烟肼在无水乙醇中反应得到席夫碱化合物N-[(1-吡嗪基)-1-亚甲基]异烟酰肼(L)。以L和硝酸银为原料,通过扩散法合成了配位聚合物{[Ag₃L₂(NO₃)₂]CH₃CN}_n,并通过X-射线单晶衍射、元素分析、红外光谱、荧光光谱对其进行结构解析和性质表征。单晶衍射分析结果表明,该配位聚合物属单斜晶系,P2₁/c空间群,晶胞参数为a=0.611 70(10) nm,b=1.347 08(3) nm,c=2.018 69(4) nm,V=1.661 06(6) nm³,Z=2,Mr=970.19,Dc=1.940 g/cm³,配体分子以银离子为连接点形成二维网状结构。荧光光谱分析表明配体和配位聚合物均有较好的发光性能,且配位聚合物荧光强度优于配体。抗菌活性表明,配位聚合物对白色葡萄球菌、藤黄八叠球菌及枯草芽孢杆菌有较好的特异性,具有良好的医药应用前景。

关键词: 吡嗪席夫碱, 银配位聚合物, 晶体结构, 荧光, 抗菌活性

Abstract: Pyrazine Schiff base derivative N-[1-(pyrazin-2-yl)ethylidene] isonicotinohydrazide(L) was obtained by the reaction of 2-acetylpyrazine and isoniazid in anhydrous ethanol. A coordination polymer {[Ag₃L₂(NO₃)₂]CH₃CN}_n was synthesized by diffusion method with the ligand and silver nitrate as raw materials, and its structure and properties were analyzed and characterized by X-ray single crystal diffraction, elemental analysis, IR, and fluorescence spectra. The results of single crystal diffraction analysis show that the complex belongs to monoclinic crystal system, P2₁/c space group, and the crystal cell parameters are a=0.611 70(10) nm, b=1.347 08(3) nm, c=2.018 69(4) nm, V=1.661 06(6) nm³, Z=2, Mr=970.19, Dc=1.940 g/cm³. The ligand molecules form a two-dimensional reticular structure with silver ions as the connecting point. Fluorescence spectrum analysis shows that both the ligand and the complex have better luminescent performance, and the fluorescence intensity of the complex is better than that of the ligand. The antibacterial activity indicates that the complex has good specificity to S. albus, S. luteus, and B. subtilis which has good prospects for medical application.

Key words: pyrazine schiff base, silver coordination polymer, crystal structure, fluorescence, antimicrobial activity

中图分类号:

O614

廖延智, 郭俊儿, 冯安生, 赖敏成, 杨超杰, 徐小云, 游遨. 吡嗪席夫碱银配位聚合物的晶体结构、发光性质和抗菌活性[J]. 人工晶体学报, 2021, 50(6): 1076-1081.

LIAO Yanzhi, GUO Juner, FENG Ansheng, LAI Mincheng, YANG Chaojie, XU Xiaoyun, YOU Ao. Crystal Structure, Luminescent Properties and Antibacterial Activity of Silver(I) Coordination Polymer with Pyrazine Schiff-Base Derivative Ligand[J]. JOURNAL OF SYNTHETIC CRYSTALS, 2021, 50(6): 1076-1081.

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