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人工晶体学报 ›› 2023, Vol. 52 ›› Issue (2): 196-207.

• 综合评述 • 上一篇    下一篇

碲锌镉器件技术进展及其在SPECT中的应用

吴忠航1,2, 孙斌2,3, 黄钢1, 屈骞4, 唐懿文2, 孙九爱2   

  1. 1.上海健康医学院上海市分子影像学重点实验室,上海 201318;
    2.上海健康医学院医学影像学院,上海 201318;
    3.海军军医大学第一附属医院,上海 200433;
    4.上海交通大学医学院附属瑞金医院核医学科,上海 200020
  • 收稿日期:2022-10-24 出版日期:2023-02-15 发布日期:2023-03-08
  • 通信作者: 孙九爱,副教授。E-mail:sunja@sumhs.edu.cn
  • 作者简介:吴忠航(1986—),男,福建省人,博士,讲师。E-mail:wuzh@sumhs.edu.cn
  • 基金资助:
    国家重大科研仪器研制项目(82127807);国家重点研发计划(2020YFA0909000);上海市分子影像学重点实验室建设项目(18DZ2260400)

Advancement of Cadmium Zinc Telluride Detector and Its Application in SPECT

WU Zhonghang1,2, SUN Bin2,3, HUANG Gang1, QU Qian4, TANG Yiwen2, SUN Jiuai2   

  1. 1. Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China;
    2. School of Medical Imaging, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China;
    3. The First Affiliated Hospital of Naval Military Medical University, Shanghai 200433, China;
    4. Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China
  • Received:2022-10-24 Online:2023-02-15 Published:2023-03-08

摘要: 核医学成像设备中的探测器是整个设备的核心部件。基于闪烁体探测器的核医学成像设备存在光电转换效率低和能量分辨率差等关键问题,短期内难以有效解决。而近年来碲锌镉半导体探测器的发展使得核医学成像设备在能量分辨率和空间分辨率等方面取得了很大的提高。本文以单光子发射计算机断层成像(SPECT)技术为例,首先介绍了核医学成像原理及设备组成,然后从碲锌镉探测器的工作原理及基本结构出发,综述了碲锌镉探测器的新技术及其在临床核医学的应用,最后结合核医学领域应用的需求展望了碲锌镉探测器的研究重点和技术发展趋势。

关键词: 碲锌镉, 探测器, 核医学, 单光子发射计算机断层成像, 能量分辨率, 光电转换效率

Abstract: Radiation detector is one of the most important components for nuclear medicine imaging equipment like single photon emission computed tomography (SPECT). Among different types of detection technologies, scintillator detectors are the most extensively used ones, but associated with some problems including slow imaging speed and poor image quality which are inherent and difficult to solve. In recent years, the advancement of new semiconductor detection technologies such as cadmium zinc telluride (CdZnTe) detectors have greatly improved the energy and spatial resolving capability of nuclear medicine imaging equipment. Based on the introduction of the working principle and main parts of nuclear medicine equipment, this paper uses the SPECT as an example to review the advancement of the CdZnTe detectors including the performance improvement in clinical nuclear medicine, and finally points out the potential research and development trends of CdZnTe detectors demanded by the nuclear medicine clinical applications.

Key words: cadmium zinc telluride, detector, nuclear medicine, SPECT, energy resolution, photoelectric conversion efficiency

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